SCHEMBL22906148

SCHEMBL22906148

Cc1c(I)cc(C=O)c(O)c1I

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 15/20 0.52
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
PIM1 P11309 1/20 0.35
MCL1 Q07820 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26857676 0.86 ERN1 (0.54) ERN1PIM1MCL1
SCHEMBL22897459 0.84 ERN1 (0.52) ERN1PIM1MCL1
SCHEMBL22897458 0.81 ERN1 (0.57) ERN1PIM1
SCHEMBL10962826 0.81 ERN1 (0.63) ERN1MEN1LMNAHTTKMT2A
SCHEMBL29425550 0.81 ERN1 (0.57) ERN1PIM1
SCHEMBL27945834 0.78 ERN1 (0.46) ERN1MEN1KMT2A
SCHEMBL23268461 0.76 ERN1 (0.52) ERN1PIM1
SCHEMBL16648398 0.76 ERN1 (0.47) ERN1
SCHEMBL26874970 0.74 MCL1 (0.53) ERN1LMNAMCL1
SCHEMBL15789359 0.74 ERN1 (0.65) ERN1PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355833-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LIMITED (GB) 2023-11-09 US disclosed
US-20230279172-A1 RADIOPAQUE POLYMERS Boston Scientific Medical Device Limited (IE) 2023-09-07 US disclosed
WO-2021009734-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LIMITED (GB) 2021-01-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230279172-A1 RADIOPAQUE POLYMERS SSTR3, VHL, PLG ERN1 2648/4885MEN1 55/4885LMNA 2329/4885
US-20230355833-A1 RADIOPAQUE POLYMERS TPO, PGLS, IQGAP1 ERN1 3496/4885MEN1 246/4885LMNA 3452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.