Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22906876 | 0.86 | OPRM1 (0.33) | OPRM1OPRL1BCHETMEM97CARM1 | |
| SCHEMBL27133585 | 0.77 | LIPG (0.37) | OPRM1OPRL1BCHEPDE4DDPP4 | |
| SCHEMBL22906875 | 0.75 | BCHE (0.36) | OPRM1OPRL1BCHETMEM97CARM1 | |
| SCHEMBL20120320 | 0.73 | CTSL (0.44) | OPRM1OPRL1BCHETMEM97CARM1 | |
| SCHEMBL20120322 | 0.73 | CTSL (0.44) | OPRM1OPRL1BCHETMEM97CARM1 | |
| SCHEMBL23205312 | 0.68 | CTSL (0.46) | OPRM1OPRL1BCHETMEM97CARM1 | |
| SCHEMBL21421849 | 0.68 | CTSL (0.46) | OPRM1OPRL1BCHETMEM97CARM1 | |
| SCHEMBL27133574 | 0.64 | CTSL (0.36) | OPRM1OPRL1BCHETMEM97CARM1 | |
| SCHEMBL16248689 | 0.64 | KDM4E (0.53) | OPRM1HRH3CHRM3 | |
| SCHEMBL20121045 | 0.64 | CTSL (0.45) | OPRM1OPRL1BCHETMEM97CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011913-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |