Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.48 |
| ▸ | WIZ | O95785 | 6/20 | 0.46 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120388 | 0.91 | CRBN (0.59) | CRBNWIZIKZF2 | |
| SCHEMBL24291214 | 0.85 | CRBN (0.61) | CRBNWIZIKZF2 | |
| SCHEMBL20231099 | 0.80 | CRBN (0.62) | CRBNWIZIKZF2 | |
| SCHEMBL20046456 | 0.80 | CRBN (0.62) | CRBNWIZIKZF2 | |
| SCHEMBL22907148 | 0.80 | WIZ (0.41) | CRBNWIZIKZF2 | |
| SCHEMBL29439985 | 0.79 | CRBN (0.64) | CRBNWIZIKZF2 | |
| SCHEMBL24501067 | 0.79 | CRBN (0.64) | CRBNWIZIKZF2 | |
| SCHEMBL24817722 | 0.79 | CRBN (0.61) | CRBNWIZIKZF2 | |
| SCHEMBL25988439 | 0.79 | CRBN (0.70) | CRBNWIZIKZF2 | |
| SCHEMBL24500580 | 0.79 | CRBN (0.63) | CRBNWIZIKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011913-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |