SCHEMBL22907468

SCHEMBL22907468

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1ccc(N(c2ccc(-n3c4ccc(C)cc4c4cc(C)ccc43)cc2)c2cccc([Si](c3ccccc3)(c3ccccc3)c3ccccc3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.37
MAPT P10636 4/20 0.34
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 3/20 0.32
FGFR1 P11362 1/20 0.32
HTT P42858 2/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
GAA P10253 1/20 0.32
GFER P55789 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
ATM Q13315 1/20 0.31
KMT2A Q03164 5/20 0.31
MEN1 O00255 4/20 0.31
HPGD P15428 2/20 0.31
POLB P06746 2/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22907471 0.96 KDM4E (0.38) APPMAPTALDH1A1SMN1; SMN2NPSR1
SCHEMBL22907469 0.93 APP (0.33) APPMAPTALDH1A1SMN1; SMN2KDM4E
SCHEMBL22907642 0.92 APP (0.33) APPMAPTPGRRORARORC
SCHEMBL13249699 0.90 APP (0.37) APPMAPTALDH1A1SMN1; SMN2NPSR1
SCHEMBL13249706 0.90 APP (0.37) APPMAPTALDH1A1SMN1; SMN2NPSR1
SCHEMBL13249698 0.89 APP (0.35) APPMAPTALDH1A1SMN1; SMN2NPSR1
SCHEMBL12879544 0.89 APP (0.36) APPMAPTALDH1A1SMN1; SMN2NPSR1
SCHEMBL22907470 0.88 RORC (0.34) APPMAPTKDM4EL3MBTL1ATM
SCHEMBL12721739 0.88 APP (0.34) APPMAPTALDH1A1SMN1; SMN2NPSR1
SCHEMBL12721694 0.88 APP (0.34) APPMAPTALDH1A1SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210020854-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-21 US disclosed