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SCHEMBL22907642

SCHEMBL22907642

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1ccc(N(c2ccc(-n3c4ccc(C(C)(C)C)cc4c4cc(C(C)(C)C)ccc43)cc2)c2cccc([Si](c3ccccc3)(c3ccccc3)c3ccccc3)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 1/20 0.33
▸ PPARG P37231 5/20 0.32
▸ PPARA Q07869 2/20 0.31
▸ MAPT P10636 1/20 0.31
▸ PGR P06401 1/20 0.31
▸ RORA P35398 1/20 0.31
▸ RORC P51449 1/20 0.31
▸ RORB Q92753 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22907641 0.95 PPARG (0.34) APPPPARGPPARAPGRRORA
SCHEMBL22907468 0.92 APP (0.37) APPMAPTPGRRORARORC
SCHEMBL22907646 0.92 PPARG (0.37) PPARGPPARAMAPTPGRRORA
SCHEMBL22907471 0.89 KDM4E (0.38) APPMAPTPGRRORARORC
SCHEMBL22907643 0.89 PTGES (0.35) PPARGPPARAMAPTPGRRORA
SCHEMBL22907469 0.86 APP (0.33) APPPPARGMAPT
SCHEMBL22907505 0.85 NOTUM (0.35) PPARGPPARAMAPTPGRRORA
SCHEMBL4400215 0.84 PPARG (0.38) APPPPARGPPARAPGRRORA
SCHEMBL22907467 0.84 RORC (0.34) PPARGPPARARORC
SCHEMBL13249699 0.83 APP (0.37) APPPPARGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210020854-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-21 — — US disclosed