SCHEMBL22907671

SCHEMBL22907671

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2ccc(N(c3ccc(-n4c5ccc(-c6ccccc6)cc5c5cc(-c6ccccc6)ccc54)cc3)c3cccc([Si](c4ccccc4)(c4ccccc4)c4ccccc4)c3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.33
NR3C1 P04150 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22907669 0.96 TSPO (0.38) TSPONR3C1KDM4EATML3MBTL1
SCHEMBL15764072 0.94 L3MBTL1 (0.41) TSPOKDM4EATML3MBTL1
SCHEMBL17463404 0.94 KDM4E (0.33) TSPOKDM4EATML3MBTL1
SCHEMBL22907469 0.93 APP (0.33) TSPONR3C1KDM4EAPP
SCHEMBL17118534 0.92 TSPO (0.36) TSPONR3C1KDM4EATML3MBTL1
SCHEMBL17118518 0.92 TSPO (0.36) TSPONR3C1KDM4EATML3MBTL1
SCHEMBL24947454 0.92 KDM4E (0.40) TSPOKDM4EATML3MBTL1
SCHEMBL22907643 0.92 PTGES (0.35) TSPO
SCHEMBL13249746 0.91 KDM4E (0.32) KDM4EATML3MBTL1APP
SCHEMBL24972164 0.91 L3MBTL1 (0.41) TSPOKDM4EATML3MBTL1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210020854-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-21 US disclosed