Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343355 | 0.82 | CA1 (0.50) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL14246988 | 0.79 | AKR1B1 (0.46) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL19620709 | 0.79 | CA1 (0.39) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL92893 | 0.78 | CA2 (0.58) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL10791482 | 0.78 | CA1 (0.52) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL17804288 | 0.78 | PRSS1 (0.58) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL22429350 | 0.78 | CA1 (0.46) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL19636161 | 0.76 | CA1 (0.44) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL13990531 | 0.76 | CA1 (0.44) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL3997489 | 0.75 | PRSS1 (0.55) | CA1CA2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3226897-B1 | ANTIBODIES TARGETING B-CELL MATURATION ANTIGEN AND METHODS OF USE | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-01-20 | — | — | EP | disclosed |