SCHEMBL17804288

SCHEMBL17804288

CS(F)(F)Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 2/20 0.58
PRSS2 P07478 2/20 0.58
PRSS3 P35030 2/20 0.58
FAAH O00519 1/20 0.58
ELANE P08246 1/20 0.58
PRTN3 P24158 1/20 0.58
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
TP53 P04637 1/20 0.43
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP13 P45452 1/20 0.41
CALM1 P0DP23 1/20 0.41
KMT2A Q03164 2/20 0.40
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1343355 0.78 CA1 (0.50) PRSS1PRSS2PRSS3FAAHELANE
SCHEMBL22908217 0.78 CA1 (0.50) PRSS1PRSS2PRSS3FAAHELANE
SCHEMBL92893 0.74 CA2 (0.58) PRSS1PRSS2PRSS3FAAHELANE
SCHEMBL22429350 0.74 CA1 (0.46) PRSS1PRSS2PRSS3FAAHELANE
SCHEMBL10791482 0.74 CA1 (0.52) PRSS1PRSS2PRSS3FAAHELANE
Phenylmethylsulfonylfluoride SCHEMBL3965163 0.74 PRSS1 (1.00) PRSS1PRSS2PRSS3FAAHELANE
Phenylmethylsulfonylfluoride SCHEMBL24938 0.74 PRSS1 (1.00) PRSS1PRSS2PRSS3FAAHELANE
Phenylmethylsulfonylfluoride SCHEMBL28507854 0.73 PRSS1 (0.86) PRSS1PRSS2PRSS3FAAHELANE
SCHEMBL19636161 0.72 CA1 (0.44) PRSS1PRSS2PRSS3FAAHELANE
Phenylmethylsulfonylfluoride SCHEMBL4869292 0.72 PRSS1 (0.95) PRSS1PRSS2PRSS3FAAHELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2443087-B1 DISUBSTITUTED-AMINODIFLUOROSULFINIUM SALTS, PROCESS FOR PREPARING SAME AND METHOD OF USE AS DEOXOFLUORINATION REAGENTS OMEGACHEM INC (CA) 2016-06-08 EP disclosed