Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908552 | 0.92 | CYP3A4 (0.44) | CCR8KCNH2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL22908431 | 0.92 | GRM3 (0.46) | ALDH1A1CYP1A2CYP2D6TSHRUSP2 | |
| SCHEMBL22908437 | 0.91 | MGLL (0.44) | CCR8KCNH2ALDH1A1LMNAHTR1A | |
| SCHEMBL24120388 | 0.91 | ALDH1A1 (0.38) | ALDH1A1CYP1A2ARMEN1KMT2A | |
| SCHEMBL21344240 | 0.90 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2D6TSHRUSP2 | |
| SCHEMBL22908553 | 0.90 | TDP1 (0.43) | CCR8KCNH2ALDH1A1CYP2D6CYP3A4 | |
| SCHEMBL22908405 | 0.88 | L3MBTL1 (0.42) | CCR8KCNH2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL22908539 | 0.87 | CCR8 (0.47) | CCR8KCNH2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL22908536 | 0.87 | CYP2D6 (0.37) | CYP1A2CYP2D6TSHRMEN1KMT2A | |
| SCHEMBL22908447 | 0.84 | HTR4 (0.34) | CCR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114080384-B | Herbicidal cyclohexanedione derivatives | 先正达农作物保护股份公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-3997072-A1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| CN-114080384-A | Herbicidal cyclohexanedione derivatives | 先正达农作物保护股份公司 | 2022-02-22 | — | — | CN | disclosed |
| WO-2021009048-A1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |