SCHEMBL22908557 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	TRPC6	Q9Y210	6/20	0.40

▸	SCN9A	Q15858	9/20	0.39

▸	HCRTR1	O43613	1/20	0.36

▸	HCRTR2	O43614	1/20	0.36

▸	HSD11B1	P28845	1/20	0.35

▸	MAPK7	Q13164	1/20	0.35

▸	USP2	O75604	1/20	0.35

▸	TSHR	P16473	1/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.35

▸	CNR1	P21554	1/20	0.35

▸	CNR2	P34972	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22908441	0.89	DRD3 (0.41)	TRPC6MAPK7
SCHEMBL22992221	0.86	SCN9A (0.41)	TRPC6SCN9AUSP2SMN1; SMN2CNR1
SCHEMBL22908444	0.86	EPHX2 (0.36)	TRPC6
SCHEMBL22908539	0.85	CCR8 (0.47)	SMN1; SMN2
SCHEMBL22908445	0.84	CYP3A4 (0.34)	USP2TSHR
SCHEMBL22908440	0.83	HTR1A (0.37)	TRPC6USP2
SCHEMBL22908554	0.83	IRAK4 (0.37)	USP2TSHRSMN1; SMN2
SCHEMBL22908432	0.82	ACACA (0.33)	SMN1; SMN2CNR2
SCHEMBL22908552	0.81	CYP3A4 (0.44)	USP2TSHRSMN1; SMN2
SCHEMBL22908536	0.80	CYP2D6 (0.37)	TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021009048-A1	HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES	SYNGENTA CROP PROTECTION AG (CH)	2021-01-21	—	—	WO	disclosed