Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22526538 | 0.88 | HRH2 (0.42) | MEN1ALDH1A1KMT2AITGB3ITGA2B | |
| SCHEMBL23560455 | 0.86 | CHRNB2 (0.37) | MEN1ALDH1A1KMT2AITGB3ITGA2B | |
| SCHEMBL24673636 | 0.86 | HRH2 (0.41) | MEN1ALDH1A1KMT2AITGB3ITGA2B | |
| SCHEMBL23806843 | 0.84 | MEN1 (0.39) | MEN1ALDH1A1KMT2AITGB3ITGA2B | |
| SCHEMBL25468751 | 0.84 | ITGB3 (0.34) | MEN1ALDH1A1KMT2AITGB3ITGA2B | |
| SCHEMBL22793897 | 0.81 | HRH2 (0.40) | MEN1ALDH1A1KMT2AITGB3ITGA2B | |
| SCHEMBL18711704 | 0.80 | ITGB3 (0.41) | MEN1ALDH1A1KMT2AITGB3ITGA2B | |
| SCHEMBL21106934 | 0.80 | CHRNB2 (0.34) | MEN1ALDH1A1KMT2AITGB3ITGA2B | |
| SCHEMBL23695839 | 0.79 | MEN1 (0.40) | MEN1ALDH1A1KMT2AITGB3ITGA2B | |
| SCHEMBL23133950 | 0.77 | NPC1 (0.45) | MEN1ALDH1A1KMT2AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011871-A1 | MERTK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |