Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909122 | 0.84 | MEN1 (0.37) | ITGB3ITGA2BLSSMEN1ALDH1A1 | |
| SCHEMBL22526538 | 0.84 | HRH2 (0.42) | ITGB3ITGA2BLSSMEN1ALDH1A1 | |
| SCHEMBL26404242 | 0.84 | LSS (0.36) | LSSMEN1ALDH1A1KMT2ANAMPT | |
| SCHEMBL24673636 | 0.82 | HRH2 (0.41) | ITGB3ITGA2BLSSMEN1ALDH1A1 | |
| SCHEMBL23560455 | 0.82 | CHRNB2 (0.37) | ITGB3ITGA2BLSSMEN1ALDH1A1 | |
| SCHEMBL23806843 | 0.80 | MEN1 (0.39) | ITGB3ITGA2BMEN1ALDH1A1KMT2A | |
| SCHEMBL22793897 | 0.77 | HRH2 (0.40) | ITGB3ITGA2BMEN1ALDH1A1KMT2A | |
| SCHEMBL25728122 | 0.77 | KDM4E (0.33) | LSSMEN1ALDH1A1KMT2ANAMPT | |
| SCHEMBL18711704 | 0.77 | ITGB3 (0.41) | ITGB3ITGA2BMEN1ALDH1A1KMT2A | |
| SCHEMBL21106934 | 0.76 | CHRNB2 (0.34) | ITGB3ITGA2BLSSMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081759-A1 | BIFUNCTIONAL PI3K-ALPHA INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |