SCHEMBL22909460

SCHEMBL22909460

CN(C)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1OC1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29729064 0.80
SCHEMBL28762128 0.77 CA1 (0.50)
SCHEMBL29899443 0.77 F2 (0.38)
SCHEMBL22909594 0.77 F2 (0.38)
SCHEMBL29899466 0.77 CA1 (0.35)
SCHEMBL22909160 0.76 MAPT (0.36)
SCHEMBL22909271 0.73 CA1 (0.43)
SCHEMBL22909259 0.72 CA1 (0.31)
SCHEMBL22909157 0.72 GSTO1 (0.32)
SCHEMBL29729037 0.72 GSTO1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559454-B2 Benzenesulfonamide derivatives and uses thereof 2692372 ONTARIO, INC. (CA) 2026-02-24 US disclosed
US-20220281812-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF 2692372 ONTARIO INC (CA) 2022-09-08 US disclosed
EP-4017843-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF 2692372 Ontario, Inc. (CA) 2022-06-29 EP disclosed
CN-114502533-A Benzenesulfonamide derivatives and use thereof 2692372安大略公司 2022-05-13 CN disclosed
WO-2021009568-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF 2692372 ONTARIO, INC. (CA) 2021-01-21 WO disclosed