Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671294 | 1.00 | MEN1 (0.50) | MEN1KMT2ALMNAALOX12CA12 | |
| SCHEMBL22909398 | 0.92 | LMNA (0.46) | MEN1KMT2ALMNAALOX12ALDH1A1 | |
| SCHEMBL29671330 | 0.92 | LMNA (0.46) | MEN1KMT2ALMNAALOX12ALDH1A1 | |
| SCHEMBL29671256 | 0.91 | ALDH1A1 (0.47) | MEN1KMT2ALMNAALOX12ALDH1A1 | |
| SCHEMBL22909505 | 0.91 | ALDH1A1 (0.47) | MEN1KMT2ALMNAALOX12ALDH1A1 | |
| SCHEMBL22909389 | 0.91 | LMNA (0.46) | MEN1KMT2ALMNAALOX12ALDH1A1 | |
| SCHEMBL29671268 | 0.91 | LMNA (0.46) | MEN1KMT2ALMNAALOX12ALDH1A1 | |
| SCHEMBL22909357 | 0.89 | PGR (0.47) | MEN1KMT2ALMNAALOX12ALDH1A1 | |
| SCHEMBL29671240 | 0.89 | PGR (0.47) | MEN1KMT2ALMNAALOX12ALDH1A1 | |
| SCHEMBL22909294 | 0.87 | LMNA (0.50) | MEN1KMT2ALMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |