Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | IL1RN | P18510 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909775 | 0.96 | ADAM17 (0.38) | KMT2AALDH1A1KDM4ETHRBLMNA | |
| SCHEMBL22909911 | 0.96 | FNTA (0.36) | KMT2AALDH1A1KDM4ETHRBLMNA | |
| SCHEMBL22909827 | 0.96 | ADAM17 (0.38) | KMT2AALDH1A1KDM4ETHRBLMNA | |
| SCHEMBL21431346 | 0.95 | ADAM17 (0.39) | KMT2AADAM17CTSLCTSSCTSK | |
| SCHEMBL21431345 | 0.94 | ADAM17 (0.40) | KMT2AALDH1A1KDM4ETHRBLMNA | |
| SCHEMBL21431349 | 0.94 | ADAM17 (0.36) | KMT2AADAM17ANPEPMMP2MMP13 | |
| SCHEMBL22909446 | 0.93 | ADAM17 (0.32) | KMT2AALDH1A1KDM4ETHRBADAM17 | |
| SCHEMBL21431347 | 0.92 | ANPEP (0.32) | KMT2AANPEPIL1RNERAP2ERAP1 | |
| SCHEMBL22909625 | 0.92 | ADAM17 (0.33) | KMT2AADAM17MMP2MMP13MMP14 | |
| SCHEMBL21431224 | 0.91 | ADAM17 (0.31) | KMT2AADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339193-B2 | CDP protein secretion inhibitors | KEZAR LIFE SCIENCES (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210017233-A1 | CDP PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339193-B2 | CDP protein secretion inhibitors | SEC61G, SEC61A1, SEC61B | KMT2A 4842/4885ALDH1A1 4805/4885KDM4E 4704/4885 |
| US-20210017233-A1 | CDP PROTEIN SECRETION INHIBITORS | SEC61G, SEC61A1, SEC61B | KMT2A 4842/4885ALDH1A1 4805/4885KDM4E 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.