Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 3/20 | 0.73 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.68 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.68 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.68 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | TSPO | P30536 | 1/20 | 0.68 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.68 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.62 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.62 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.62 |
| ▸ | CETP | P11597 | 1/20 | 0.62 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3768316 | 1.00 | PLA2G4A (0.73) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL23925264 | 0.87 | PLA2G4A (0.67) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL3772063 | 0.87 | SPHK2 (0.62) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL5500454 | 0.83 | S1PR4 (0.75) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL13030815 | 0.83 | S1PR4 (0.75) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL18993886 | 0.82 | S1PR4 (0.73) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| Dimethylspingosine SCHEMBL19745875 | 0.82 | SPHK2 (0.86) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL20798182 | 0.81 | S1PR1 (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL22910837 | 0.81 | S1PR1 (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL17482409 | 0.81 | S1PR1 (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210015767-A1 | ARTIFICIALLY SYNTHESIZED SPHINGOSINE DERIVATIVE LIPOID MONOMER AND USE OF SAME FOR DELIVERING NUCLEIC ACID | BEIJING BAISHIHEKANG PHARMACEUTICAL TECHNOLOGY (BSJPHARMA) CO., LTD (CN) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210015767-A1 | ARTIFICIALLY SYNTHESIZED SPHINGOSINE DERIVATIVE LIPOID MONOMER AND USE OF SAME FOR DELIVERING NUCLEIC ACID | SPHK2, SPHK1, S1PR2 | PLA2G4A 65/4885S1PR4 5/4885S1PR1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.