Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 3/20 | 0.67 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.65 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.65 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.65 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TSPO | P30536 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.60 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911020 | 0.87 | PLA2G4A (0.73) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL3768316 | 0.87 | PLA2G4A (0.73) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL13030815 | 0.81 | S1PR4 (0.75) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL5500454 | 0.81 | S1PR4 (0.75) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL18993886 | 0.80 | S1PR4 (0.73) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL29455695 | 0.80 | SPHK2 (0.70) | ALDH1A1SPHK2SPHK1CETP | |
| SCHEMBL3777505 | 0.80 | S1PR1 (0.68) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL20798182 | 0.79 | S1PR1 (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL22910837 | 0.79 | S1PR1 (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL3885 | 0.79 | S1PR1 (1.00) | PLA2G4AS1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021207858-A1 | DIAGNOSIS AND TREATMENT OF COVID-19 | LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (CA) | 2021-10-21 | — | — | WO | disclosed |