Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 15/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912212 | 0.90 | SDHB (0.46) | SDHBMAPTPOLB | |
| SCHEMBL19805936 | 0.87 | SDHB (0.43) | SDHBMAPT | |
| SCHEMBL20985722 | 0.86 | SDHB (0.73) | SDHB | |
| SCHEMBL29976388 | 0.85 | SDHB (0.56) | SDHBTSHR | |
| SCHEMBL19805750 | 0.85 | SDHB (0.56) | SDHBTSHR | |
| SCHEMBL22912229 | 0.85 | SDHB (0.41) | SDHBMAPT | |
| SCHEMBL20985695 | 0.83 | SDHB (0.65) | SDHBMAPTPOLB | |
| SCHEMBL19805906 | 0.83 | SDHB (0.71) | SDHBMAPTPOLB | |
| SCHEMBL22912217 | 0.82 | SDHB (0.69) | SDHBMAPTPOLB | |
| SCHEMBL19805969 | 0.82 | SDHB (0.70) | SDHBMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |