Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29976626 | 0.85 | SDHB (0.51) | SDHBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20985638 | 0.85 | SDHB (0.51) | SDHBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22912253 | 0.85 | SDHB (0.57) | SDHBMAPT | |
| SCHEMBL22912212 | 0.85 | SDHB (0.46) | SDHBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL19805936 | 0.83 | SDHB (0.43) | SDHBMAPTGAALMNAPDE4A | |
| SCHEMBL22912230 | 0.82 | SDHB (0.47) | SDHBMAPTGAALMNANPSR1 | |
| SCHEMBL19806089 | 0.78 | SDHB (0.49) | SDHBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL21019878 | 0.75 | SDHB (0.61) | SDHBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19805741 | 0.75 | SDHB (0.58) | SDHBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29976277 | 0.75 | SDHB (0.58) | SDHBPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |