Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 11/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | FUBP1 | Q96AE4 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985627 | 0.88 | SDHB (0.54) | SDHBSMN1; SMN2 | |
| SCHEMBL29976298 | 0.87 | SDHB (0.42) | SDHBMAPTKDM4EALDH1A1HTT | |
| SCHEMBL19805932 | 0.87 | SDHB (0.42) | SDHBMAPTKDM4EALDH1A1HTT | |
| SCHEMBL22912212 | 0.87 | SDHB (0.46) | SDHBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL22912253 | 0.87 | SDHB (0.57) | SDHBMAPT | |
| SCHEMBL22912229 | 0.83 | SDHB (0.41) | SDHBMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL26313265 | 0.78 | SDHB (0.52) | SDHBMAPTKDM4EALDH1A1HTT | |
| SCHEMBL26313272 | 0.76 | SDHB (0.68) | SDHB | |
| SCHEMBL29976277 | 0.76 | SDHB (0.58) | SDHBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19805741 | 0.76 | SDHB (0.58) | SDHBPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |