Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10263887 | 0.93 | CA12 (0.48) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL21795443 | 0.76 | CA12 (0.46) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL21207441 | 0.71 | ALDH1A1 (0.43) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL22093201 | 0.71 | CA12 (0.50) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL19592402 | 0.70 | HTR7 (0.34) | TSHRL3MBTL1 | |
| SCHEMBL1107023 | 0.70 | CA12 (0.54) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL7602303 | 0.69 | CA12 (0.59) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL26541961 | 0.69 | ALDH1A1 (0.44) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL28263344 | 0.68 | TSHR (0.51) | SMN1; SMN2TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4547019 | 0.67 | ALDH1A1 (0.61) | CA12CA7CA14SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021016263-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2021-01-28 | — | — | WO | disclosed |