Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31005942 | 0.82 | SLC6A7 (0.49) | CNR2SLC6A7ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12607645 | 0.82 | SLC6A7 (0.49) | CNR2SLC6A7ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1834829 | 0.80 | CYP1A2 (0.50) | CNR2SLC6A7ALDH1A1HPGDMAPK1 | |
| SCHEMBL5754979 | 0.79 | ALDH1A1 (0.61) | MEN1NPC1RAB9AKMT2ACNR2 | |
| SCHEMBL2102567 | 0.78 | SLC6A7 (0.47) | MEN1KMT2ASLC6A7MAPTNPSR1 | |
| SCHEMBL2001725 | 0.78 | SLC6A7 (0.47) | MEN1KMT2ASLC6A7MAPTNPSR1 | |
| SCHEMBL27040079 | 0.78 | ALDH1A1 (0.48) | NPC1RAB9AKMT2ASLC6A7HTT | |
| SCHEMBL29999093 | 0.77 | PLD1 (0.59) | SLC6A7HTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL907776 | 0.77 | HTT (0.44) | MEN1NPC1RAB9AKMT2ACNR2 | |
| SCHEMBL9557856 | 0.77 | HTR3A (0.53) | SLC6A7ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163380-A1 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-08 | — | — | WO | claimed |
| CN-102234286-A | Condensed heteroaryl derivatives | ALLIST PHARMACEUTICALS INC | 2011-11-09 | — | — | CN | claimed |
| EP-1266651-B1 | UV absorbing and photostabilizing agents and compositions and external preparation for skin | SHISEIDO CO LTD (JP) | 2006-09-06 | — | — | EP | claimed |
| WO-2024133200-A1 | P2X3 RECEPTOR ANTAGONISTS | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2024-06-27 | — | — | WO | disclosed |
| EP-4323351-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | A2A Pharmaceuticals, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| CN-117460724-A | Compositions and methods for treating cancer | A2A制药有限公司 | 2024-01-26 | — | — | CN | disclosed |
| WO-2022221194-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | A2A PHARMACEUTICALS, INC. (US) | 2022-10-20 | — | — | WO | disclosed |
| EP-2057133-B1 | DI-AMINO-SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC (US) | 2014-08-20 | — | — | EP | disclosed |
| US-8415350-B2 | Benzoyl-piperidine derivatives as dual modulators of the 5-HT2A and D3 receptors | HOFFMANN-LA ROCHE INC. (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120004208-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | GOBBI LUCA (CH) | 2012-01-05 | — | — | US | disclosed |
| CN-102234286-A | Condensed heteroaryl derivatives | ALLIST PHARMACEUTICALS INC | 2011-11-09 | — | — | CN | disclosed |
| EP-1266651-B1 | UV absorbing and photostabilizing agents and compositions and external preparation for skin | SHISEIDO CO LTD (JP) | 2006-09-06 | — | — | EP | disclosed |
| US-6676932-B2 | CONTAINING PYRIDAZINE DERIVATIVE SUNSCREEN AGENT | SHISEIDO CO., LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004208-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HTR2A, HTR3A, HTR2C | MEN1 3878/4885NPC1 4131/4885RAB9A 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.