SCHEMBL2291386

SCHEMBL2291386

Cc1ccc(OCc2ccccc2Br)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.59
FFAR1 O14842 3/20 0.55
FFAR4 Q5NUL3 3/20 0.55
ANO1 Q5XXA6 1/20 0.51
IDO1 P14902 2/20 0.50
KCNH2 Q12809 1/20 0.47
LMNA P02545 1/20 0.46
MAOB P27338 3/20 0.45
ALDH1A1 P00352 3/20 0.45
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
OPRD1 P41143 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1549058 0.86 KCNH2 (0.55) FFAR1FFAR4KCNH2LMNAMAOB
SCHEMBL1259945 0.84 PARP10 (0.62) PARP10FFAR1FFAR4IDO1KCNH2
SCHEMBL2293600 0.82 FFAR4 (0.60) PARP10FFAR1FFAR4IDO1LMNA
SCHEMBL2292141 0.81 PARP10 (0.59) PARP10FFAR1FFAR4IDO1MAOB
SCHEMBL8846366 0.81 PARP10 (0.59) PARP10FFAR1FFAR4ANO1IDO1
SCHEMBL10452980 0.81 MAOB (0.65) FFAR1FFAR4KCNH2LMNAMAOB
SCHEMBL2290158 0.81 MAOB (0.54) PARP10FFAR1FFAR4ANO1IDO1
SCHEMBL2294503 0.81 PARP10 (0.55) PARP10FFAR1FFAR4IDO1LMNA
SCHEMBL2291091 0.81 PARP10 (0.55) PARP10FFAR1FFAR4IDO1MAOB
SCHEMBL2292282 0.80 FFAR4 (0.65) PARP10FFAR1FFAR4IDO1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2149545-B1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2016-10-05 EP disclosed
US-7994367-B2 Method for producing benzaldehyde compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-09 US disclosed
US-20100210879-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
EP-2149545-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210879-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND NQO1, C9, TRPA1 PARP10 167/4885FFAR1 3643/4885FFAR4 3092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.