Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.59 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259945 | 0.88 | PARP10 (0.62) | PARP10FFAR1FFAR4IDO1ALDH1A1 | |
| SCHEMBL2291386 | 0.81 | PARP10 (0.59) | PARP10FFAR1FFAR4IDO1ALDH1A1 | |
| SCHEMBL2292141 | 0.81 | PARP10 (0.59) | PARP10FFAR1FFAR4IDO1ALDH1A1 | |
| SCHEMBL2293600 | 0.79 | FFAR4 (0.60) | PARP10FFAR1FFAR4IDO1ALDH1A1 | |
| SCHEMBL38654647 | 0.78 | MAOB (0.65) | PARP10IDO1GSTP1 | |
| SCHEMBL5606933 | 0.77 | PARP10 (0.55) | PARP10FFAR1FFAR4IDO1ALDH1A1 | |
| SCHEMBL2294503 | 0.77 | PARP10 (0.55) | PARP10FFAR1FFAR4IDO1ALDH1A1 | |
| SCHEMBL15774723 | 0.77 | ALDH1A1 (0.59) | PARP10FFAR1FFAR4IDO1ALDH1A1 | |
| SCHEMBL2291091 | 0.77 | PARP10 (0.55) | PARP10FFAR1FFAR4IDO1ALDH1A1 | |
| SCHEMBL17201429 | 0.77 | CYP1A2 (0.54) | PARP10FFAR1FFAR4IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693859-A | REACTING ORTHO-SUBSTITUTED PHENYL ALPHA-KETO ACID HALIDE WITH AN AMINE YIELDS SUBSTITUTED PHENYL ALPHA-KETAMIDE | SHIONOGI & CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0535928-B1 | Process for producing intermediates for use in production of alkoxyiminoacetamides | SHIONOGI & CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5502252-A | FUNGICIDES FOR RICE AND CUCUMBERS | SHIONOGI & CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5387714-A | Alpha-keto acid halide intermediate | SHIONOGI & CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0535928-A2 | Process for producing intermediates for use in production of alkoxyiminoacetamides | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-04-07 | — | — | EP | disclosed |