SCHEMBL229147

SCHEMBL229147

N#Cc1ccc(F)c(F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 4/20 0.44
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRA5 P31644 1/20 0.42
GABRA3 P34903 1/20 0.42
GAA P10253 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KIF11 P52732 1/20 0.42
GRM5 P41594 1/20 0.41
CYP2A6 P11509 2/20 0.40
ALDH1A1 P00352 1/20 0.40
CA12 O43570 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
IMPDH2 P12268 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29416796 1.00 EGLN2 (0.44) EGLN2GABRG2GABRB3GABRA5GABRA3
Benzonitrile SCHEMBL29023665 0.89 TSHR (0.58) EGLN2GABRG2GABRB3GABRA5GABRA3
SCHEMBL18361192 0.82 PTGDR2 (0.46) EGLN2GABRG2GABRB3GABRA5GABRA3
SCHEMBL924361 0.80 TRPV4 (0.45) EGLN2KIF11CYP2A6ALDH1A1CA12
SCHEMBL1797379 0.80 TRPV4 (0.59) EGLN2CYP11B1CYP11B2IMPDH2IMPDH1
SCHEMBL20792031 0.80 EGLN2 (0.49) EGLN2GABRG2GABRB3GABRA5GABRA3
SCHEMBL8731805 0.78 KIF11 (0.39) EGLN2KIF11CYP2A6ALDH1A1CA12
SCHEMBL10503719 0.78 TRPV4 (0.48) EGLN2KIF11CYP2A6ALDH1A1CA12
SCHEMBL2326230 0.78 TTR (0.41) EGLN2KIF11CYP2A6ALDH1A1CA12
SCHEMBL156405 0.78 MEN1 (0.41) EGLN2KIF11CYP2A6ALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
EP-3315579-B1 SURFACE TREATMENT AGENT INCLUDING PERFLUORO(POLY)ETHER GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2024-05-01 EP claimed
CN-117945917-A Preparation method of 3-fluoro-4-nitrobenzoic acid 衢州康鹏化学有限公司 2024-04-30 CN claimed
CN-115178220-B Synthesis device and method for preparing cyhalofop-butyl 甘肃联凯生物科技有限公司 2024-04-26 CN claimed
CN-117790893-A Electrolyte and lithium battery containing same 蜂巢能源科技股份有限公司 2024-03-29 CN claimed
CN-117756671-A Continuous reaction and separation process of 3, 4-difluorobenzonitrile 郑州大学 2024-03-26 CN claimed
CN-115490617-B Preparation process of cyhalofop-butyl with low cost and high optical purity content 江苏丰山生化科技有限公司 2024-03-26 CN claimed
CN-104387294-A PROCESS FOR THE MANUFACTURE OF R-(+)-2-(4-(4-CYANO-2-FLUOROPHENOXY)PHENOXY)PROPIONIC ACID ESTERS DOW AGROSCIENCES LLC 2015-03-04 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-8071804-B2 Process for the manufacture of R-(+)-2-(4-(4-cyano-2-fluorophenoxy)phenoxy)propionic acid esters DOW AGROSCIENCES LLC (US) 2011-12-06 US claimed
US-20110207000-A1 Nitrile additive for non-aqueous electrolyte rechargeable electrochemical cells UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY, THE 2011-08-25 US claimed
US-20110152560-A1 PROCESS FOR THE MANUFACTURE OF R-(+)-2-(4-(4-CYANO-2-FLUOROPHENOXY)PHENOXY)PROPIONIC ACID ESTERS DOW AGROSCIENCES LLC (US) 2011-06-23 US claimed
CN-101835742-A Improved process for the preparation of R- (+) -2- (4- (4-cyano-2-fluorophenoxy) phenoxy) propanoic acid esters DOW AGROSCIENCES LLC 2010-09-15 CN claimed
US-20090112015-A1 PROCESS FOR THE MANUFACTURE OF R-(+)-2-(4-(4-CYANO-2-FLUOROPHENOXY)PHENOXY)PROPIONIC ACID ESTERS DOW AGROSCIENCES LLC (US) 2009-04-30 US claimed
WO-2009055278-A1 IMPROVED PROCESS FOR THE MANUFACTURE OF R-(+)-2-(4-(4-CYANO-2-FLUOROPHENOXY)PHENOXY)PROPIONIC ACID ESTERS DOW AGROSCIENCES LLC (US) 2009-04-30 WO claimed
EP-0302203-B1 HERBICIDAL FLUOROPHENOXYPHENOXYALKANOIC ACIDS AND DERIVATIVES THEREOF DOWELANCO (US) 1992-10-28 EP claimed
EP-0302203-A1 Herbicidal fluorophenoxyphenoxyalkanoic acids and derivatives thereof DOWELANCO (US) 1989-02-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090112015-A1 PROCESS FOR THE MANUFACTURE OF R-(+)-2-(4-(4-CYANO-2-FLUOROPHENOXY)PHENOXY)PROPIONIC ACID ESTERS GNPAT, MPHOSPH6, MRTO4 EGLN2 1616/4885GABRG2 2796/4885GABRB3 2745/4885
US-20110152560-A1 PROCESS FOR THE MANUFACTURE OF R-(+)-2-(4-(4-CYANO-2-FLUOROPHENOXY)PHENOXY)PROPIONIC ACID ESTERS GNPAT, CYP4F11, CYP4F2 EGLN2 1378/4885GABRG2 2115/4885GABRB3 1265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.