SCHEMBL156405

SCHEMBL156405

N#Cc1ccc(Br)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
TTR P02766 1/20 0.41
ALB P02768 1/20 0.41
KMT2A Q03164 1/20 0.41
KIF11 P52732 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
EGLN2 Q96KS0 4/20 0.37
PTPN1 P18031 2/20 0.37
PTPN2 P17706 1/20 0.37
KDM1A O60341 2/20 0.37
KCNH2 Q12809 2/20 0.37
KDM1B Q8NB78 1/20 0.37
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
CYP2A6 P11509 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CA12 O43570 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30376222 1.00 MEN1 (0.41) MEN1TTRALBKMT2AKIF11
SCHEMBL31195817 0.82 MEN1 (0.46) MEN1TTRALBKMT2AKIF11
SCHEMBL283614 0.82 MEN1 (0.46) MEN1TTRALBKMT2AKIF11
SCHEMBL29416796 0.78 EGLN2 (0.44) KIF11EGLN2CYP11B1CYP11B2CYP2A6
SCHEMBL229147 0.78 EGLN2 (0.44) KIF11EGLN2CYP11B1CYP11B2CYP2A6
SCHEMBL11017920 0.78 MEN1 (0.52) MEN1TTRALBKMT2AMAOA
SCHEMBL16962228 0.77 KDM1A (0.37) KIF11KDM1AKCNH2KDM1B
SCHEMBL1129232 0.77 KDM1A (0.37) KIF11PTPN1KDM1AKCNH2KDM1B
SCHEMBL31235647 0.74 MEN1 (0.43) MEN1TTRALBKMT2AMAOA
SCHEMBL506682 0.74 TTR (0.54) MEN1TTRALBKMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 600 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113548982-B Preparation method of 4-cyano-2-fluorobenzyl alcohol 上海三牧化工技术有限公司 2022-05-06 CN claimed
CN-113548982-A Preparation method of 4-cyano-2-fluorobenzyl alcohol 上海三牧化工技术有限公司 2021-10-26 CN claimed
JP-4029976-A None JP disclosed
US-20260138974-A1 POTENT AND SELECTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS LEUKOS BIOTECH S L (ES) 2026-05-21 US disclosed
WO-2026090589-A1 HETEROCYCLIC HBS1L DEGRADERS TANGO THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
EP-4121421-B1 BIARYL DERIVATIVES AS YAP/TAZ-TEAD PROTEIN-PROTEIN INTERACTION INHIBITORS NOVARTIS AG (CH) 2026-03-11 EP disclosed
US-12565490-B2 Inhibitors of Receptor Interacting Protein Kinase I for the treatment of disease BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-03-03 US disclosed
EP-3826722-B1 ISOQUINOLINE COMPOUNDS AND USES THEREOF HOFFMANN LA ROCHE (CH) 2026-02-18 EP disclosed
EP-4688144-A1 COMPOUNDS AS GLP-1R AGONISTS Terns Pharmaceuticals, Inc. (US) 2026-02-11 EP disclosed
US-12540133-B2 Potent and selective compounds as serotonin 1B receptor modulators LEUKOS BIOTECH, S.L. (ES) 2026-02-03 US disclosed
US-12509431-B2 1,4-dihydroquinazolinone compounds and uses thereof EDGEWISE THERAPEUTICS, INC. (US) 2025-12-30 US disclosed
EP-0391591-B1 Pyrimidine derivative and liquid crystal composition incorporating the same SEIKO EPSON CORP (JP) 1994-06-15 EP disclosed
US-5238599-A Low threshold voltage, low driving voltage SEIKO EPSON CORPORATION (JP) 1993-08-24 US disclosed
US-5200110-A Electro-optical displays; heat resistance, dielectrics, low driving voltage, dielectrics SEIKO EPSON CORPORATION (JP) 1993-04-06 US disclosed
JP-H0429976-A PYRIMIDINE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME SEIKO EPSON CORP 1992-01-31 JP disclosed
EP-0400861-A1 1,3-dioxane derivative and liquid crystal composition incorporating the same SEIKO EPSON CORPORATION (JP) 1990-12-05 EP disclosed
EP-0391591-A2 Pyrimidine derivative and liquid crystal composition incorporating the same SEIKO EPSON CORPORATION (JP) 1990-10-10 EP disclosed
US-4784471-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-11-15 US disclosed
EP-0211876-A1 FLUOROBENZENE DERIVATIVES MERCK PATENT GmbH (DE) 1987-03-04 EP disclosed
WO-1986004895-A1 FLUOROBENZENE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-08-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138974-A1 POTENT AND SELECTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS HTR3B, HTR1B, HTR1A MEN1 2528/4885TTR 3275/4885ALB 4719/4885
US-12540133-B2 Potent and selective compounds as serotonin 1B receptor modulators HTR3B, HTR1A, HTR1B MEN1 2296/4885TTR 4103/4885ALB 4825/4885
US-12509431-B2 1,4-dihydroquinazolinone compounds and uses thereof TNNT2, TNNI3, TNNC1 MEN1 3410/4885TTR 727/4885ALB 3878/4885
US-12565490-B2 Inhibitors of Receptor Interacting Protein Kinase I for the treatment of disease RIPK1, RIPK4, RIPK2 MEN1 4734/4885TTR 2748/4885ALB 4007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.