Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.64 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.64 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91274 | 0.91 | KCNA3 (0.67) | LTA4HPLA2G2AKCNA3TAAR1ALDH1A1 | |
| SCHEMBL5375466 | 0.89 | LTA4H (0.68) | LTA4HPLA2G2AKCNA3TSHRTAAR1 | |
| SCHEMBL4515786 | 0.89 | KCNA3 (0.73) | LTA4HPLA2G2AKCNA3TAAR1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL2762681 | 0.89 | KCNA3 (0.64) | LTA4HPLA2G2AKCNA3TAAR1ALDH1A1 | |
| SCHEMBL4896604 | 0.88 | LTA4H (0.67) | LTA4HPLA2G2AKCNA3HRH3PPARA | |
| SCHEMBL8671305 | 0.86 | LTA4H (0.75) | LTA4HPLA2G2AKCNA3TSHRTAAR1 | |
| SCHEMBL8536661 | 0.86 | LTA4H (0.65) | LTA4HPLA2G2AKCNA3HRH3PPARA | |
| SCHEMBL8140756 | 0.83 | NPC1 (0.47) | LTA4HPLA2G2AKCNA3TAAR1ALDH1A1 | |
| SCHEMBL1547955 | 0.83 | LSS (0.56) | LTA4HKCNA3HRH3ALDH1A1RECQL | |
| Anisole SCHEMBL27811552 | 0.81 | CA4 (0.58) | LTA4HKCNA3TSHRTAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265458-A | Benzothiophene derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-06-20 | — | — | CN | disclosed |
| US-7989480-B2 | Aryl amino acid derivatives as inhibitors for treating inflammation | DECODE GENETICS EHF (IS) | 2011-08-02 | — | — | US | disclosed |
| EP-2066800-A2 | ARYL AMINO ACID DERIVATIVES AS INHIBITORS OF LTA4H (LEUKOTRIENE A4 HYDROLASE) FOR TREATING INFLAMMATION | Decode Genetics EHF (IS) | 2009-06-10 | — | — | EP | disclosed |
| US-20080207685-A1 | Heterocyclic Compounds As Modulators Of Peroxisome Proliferator Activated Receptors, Useful For The Treatment And/Or Prevention Of Disorders Modulated By A Ppar | ELI LILLY AND COMPANY (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207685-A1 | Heterocyclic Compounds As Modulators Of Peroxisome Proliferator Activated Receptors, Useful For The Treatment And/Or Prevention Of Disorders Modulated By A Ppar | ELI LILLY AND COMPANY (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080167310-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | GOSSETT LYNN STACY | 2008-07-10 | — | — | US | disclosed |
| US-20080167310-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | GOSSETT LYNN STACY | 2008-07-10 | — | — | US | disclosed |
| US-20080167310-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | GOSSETT LYNN STACY | 2008-07-10 | — | — | US | disclosed |
| WO-2008019306-A2 | ARYL AMINO ACID DERIVATIVES AS INHIBITORS OF LTA4H (LEUKOTRIENE A4 HYDROLASE) FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2008-02-14 | — | — | WO | disclosed |
| US-20080033024-A1 | ARYL AMINO ACID DERIVATIVES AS INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF. (IS) | 2008-02-07 | — | — | US | disclosed |
| US-4879292-A | Certain-phenoxy-phenoxy-alkylene-oxy-pyrimidines or symmetrical triazines, thio-analogues thereof, having insecticidal activity | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0128648-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4751225-A | Certain 2-pyridyloxy-lower alkylene-oxy-phenoxy compounds, thio-and methylene analogues having insecticidal properties | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0089115-B1 | OXIME ETHERS, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-05-22 | — | — | EP | disclosed |
| US-4514406-A | INSECTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-04-30 | — | — | US | disclosed |
| EP-0071463-B1 | THIOLCARBAMATE COMPOUNDS, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-04-10 | — | — | EP | disclosed |
| EP-0128648-A1 | Nitrogen-containing heterocyclic compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |
| US-4486449-A | INSECTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-04 | — | — | US | disclosed |
| EP-0089115-A1 | Oxime ethers, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-09-21 | — | — | EP | disclosed |
| EP-0071463-A1 | Thiolcarbamate compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033024-A1 | ARYL AMINO ACID DERIVATIVES AS INHIBITORS FOR TREATING INFLAMMATION | LTA4H, LTB4R2, LTB4R | LTA4H 1/4885PLA2G2A 474/4885KCNA3 1502/4885 |
| US-20080167310-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | PPARG, PPARA, PPARD | LTA4H 2191/4885PLA2G2A 2153/4885KCNA3 2792/4885 |
| US-20080207685-A1 | Heterocyclic Compounds As Modulators Of Peroxisome Proliferator Activated Receptors, Useful For The Treatment And/Or Prevention Of Disorders Modulated By A Ppar | PPARG, PPARD, PPARA | LTA4H 1937/4885PLA2G2A 2672/4885KCNA3 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.