SCHEMBL229158

SCHEMBL229158

CC(=O)N1CCC(C(=O)Cl)CC1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
EPHX2 P34913 8/20 0.44
EPHX1 P07099 4/20 0.44
KDM4E B2RXH2 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CHRNB2 P17787 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
CHRNB3 Q05901 1/20 0.40
CHRNA6 Q15825 1/20 0.40
QDPR P09417 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL693967 0.98 EPHX2 (0.43) CYP1A2TDP1EPHX2EPHX1KDM4E
SCHEMBL11850495 0.83 CYP1A2 (0.50) CYP1A2TDP1EPHX2EPHX1KDM4E
SCHEMBL190928 0.81 CYP1A2 (0.48) CYP1A2TDP1EPHX2EPHX1KDM4E
SCHEMBL8947886 0.79 LMNA (0.55) CYP1A2TDP1EPHX2EPHX1
SCHEMBL191353 0.79 LMNA (0.55) CYP1A2TDP1EPHX2EPHX1
SCHEMBL12036175 0.79 CYP1A2 (0.46) CYP1A2TDP1EPHX2EPHX1KDM4E
SCHEMBL5184241 0.79 MAPT (0.38)
SCHEMBL18711893 0.79 CYP1A2 (0.46) CYP1A2TDP1EPHX2EPHX1KDM4E
SCHEMBL18812726 0.77 CYP1A2 (0.44) CYP1A2TDP1EPHX2EPHX1KDM4E
SCHEMBL14627318 0.77 CYP1A2 (0.44) CYP1A2TDP1EPHX2EPHX1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111518019-B Preparation method of paliperidone palmitate intermediate 江苏豪森药业集团有限公司 2023-10-24 CN claimed
CN-111518019-A Preparation method of paliperidone palmitate intermediate 江苏豪森药业集团有限公司 2020-08-11 CN claimed
CN-101921224-B 1-(3-aminopropyl) piperazine-4-aminoamide compound as well as preparation method and application thereof INST BIOENGINEERING AMMS 2012-01-18 CN claimed
CN-101921224-A 1-(3-aminopropyl) piperazine-4-aminoamide compound as well as preparation method and application thereof INST BIOENGINEERING AMMS 2010-12-22 CN claimed
EP-4729059-A2 THIAZOLO [5,4-B] PYRIDINE MALT-1 INHIBITORS Abbvie Inc. (US) 2026-04-22 EP disclosed
EP-4707276-A2 MALT1 MODULATORS AND USES THEREOF Rarefied Biosciences, Inc. (US) 2026-03-11 EP disclosed
CN-116916924-B MALT1 modulators and uses thereof 稀有生物科学股份有限公司 2026-02-27 CN disclosed
EP-4499611-B1 MALT1 MODULATORS AND USES THEREOF RAREFIED BIOSCIENCES INC (US) 2026-02-18 EP disclosed
US-20250326738-A1 MALT1 Modulators and Uses Thereof RAREFIED BIOSCIENCES, INC. (US) 2025-10-23 US disclosed
EP-4547658-A1 WEE1 DEGRADING COMPOUNDS AND USES THEREOF Bristol-Myers Squibb Company (US) 2025-05-07 EP disclosed
CN-119855821-A Thiazolo [5,4-b ] pyridine MALT-1 inhibitors 艾伯维公司 2025-04-18 CN disclosed
US-20250084099-A1 THIAZOLO[5,4-B]PYRIDINE MALT-1 INHIBITORS ABBVIE INC (US) 2025-03-13 US disclosed
US-4342870-A SEROTONIN ANTAGONISTS JANSSEN PHARMACEUTICA N.V. (BE) 1982-08-03 US disclosed
EP-0037265-A1 3-(1-piperidinylalkyl)-4H-pyrido(1,2-a)pyrimidin-4-one derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1981-10-07 EP disclosed
US-4151285-A ANTICONVULSANT, ANTI-ANXIETY AGENTS A. H. ROBINS COMPANY, INC. (US) 1979-04-24 US disclosed
US-4110459-A ANALGESIC AMERICAN HOECHST CORPORATION (US) 1978-08-29 US disclosed
US-4101663-A ANTIHYPERTENSIVES AMERICAN HOECHST CORPORATION (US) 1978-07-18 US disclosed
US-4054570-A NEUROLEPTIC AGENTS CIBA-GEIGY CORPORATION (US) 1977-10-18 US disclosed
US-4046900-A TRANQUILIZERS, HYPOTENSIVES, ANALGESICS AMERICAN HOECHST CORPORATION (US) 1977-09-06 US disclosed
US-3992546-A 4-Piperidinobutyrophenones as neuroleptics CIBA-GEIGY CORPORATION (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250326738-A1 MALT1 Modulators and Uses Thereof MALT1, SQSTM1, PPP1R10 CYP1A2 3396/4885TDP1 1025/4885EPHX2 4423/4885
US-20250084099-A1 THIAZOLO[5,4-B]PYRIDINE MALT-1 INHIBITORS MALT1, PTP4A1, AMY1A CYP1A2 457/4885TDP1 523/4885EPHX2 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.