Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 6/20 | 0.31 |
| ▸ | MMP3 | P08254 | 5/20 | 0.31 |
| ▸ | MMP9 | P14780 | 5/20 | 0.31 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | MMP7 | P09237 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MMP20 | O60882 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | MMP10 | P09238 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | MMP15 | P51511 | 1/20 | 0.31 |
| ▸ | MMP16 | P51512 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23317938 | 0.83 | POLB (0.39) | POLBMMP1MMP3MMP9MMP2 | |
| SCHEMBL20143489 | 0.82 | EPHX1 (0.35) | KDM4E | |
| SCHEMBL22664190 | 0.78 | — | — | |
| SCHEMBL20806664 | 0.76 | MAOA (0.30) | DPP4 | |
| SCHEMBL13821724 | 0.76 | ALDH1A1 (0.43) | POLBALDH1A1KDM4E | |
| SCHEMBL10211145 | 0.76 | POLB (0.40) | POLBALDH1A1PIK3CDKDM4EHDAC2 | |
| SCHEMBL10031576 | 0.76 | ALDH1A1 (0.43) | POLBALDH1A1KDM4E | |
| SCHEMBL4141413 | 0.76 | ALDH1A1 (0.43) | POLBALDH1A1KDM4E | |
| SCHEMBL18977442 | 0.75 | POLB (0.43) | POLBDPP4MMP1ALDH1A1PIK3CD | |
| SCHEMBL13575257 | 0.75 | POLB (0.43) | POLBDPP4MMP1ALDH1A1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201355-A1 | IL-2 SEQUENCES AND USES THEREOF | Ascendis Pharma Oncology Division A/S (DK) | 2023-06-29 | — | — | US | disclosed |
| US-20210024602-A1 | IL-2 Conjugates | Ascendis Pharma Oncology Division A/S (DK) | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230201355-A1 | IL-2 SEQUENCES AND USES THEREOF | IL2, IL2RA, IL4I1 | POLB 1754/4885DPP4 4187/4885MMP1 1917/4885 |
| US-20210024602-A1 | IL-2 Conjugates | IL2, IL2RA, IL15 | POLB 4766/4885DPP4 1981/4885MMP1 2290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.