Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26998921 | 1.00 | LMNA (0.37) | LMNAKDM4EHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL22169085 | 0.83 | CREBBP (0.33) | LMNAGAA | |
| SCHEMBL4393000 | 0.81 | KMT2A (0.42) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL25045433 | 0.81 | KMT2A (0.42) | KDM4EHSD17B10CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL22169187 | 0.81 | GAA (0.34) | LMNAGAA | |
| SCHEMBL6506166 | 0.77 | KDM4E (0.45) | LMNAKDM4EHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL815103 | 0.76 | LMNA (0.58) | LMNAKDM4EHSD17B10MAPTALDH1A1 | |
| SCHEMBL905284 | 0.76 | LMNA (0.58) | LMNAKDM4EHSD17B10MAPTALDH1A1 | |
| SCHEMBL80480 | 0.76 | LMNA (0.58) | LMNAKDM4EHSD17B10MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL29400035 | 0.75 | LMNA (0.57) | LMNAKDM4EHSD17B10CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001141-A1 | KRAS G12D INHIBITORS AND USES THEREOF | SHANGHAI ZION PHARMA CO. LIMITED (CN) | 2023-01-26 | — | — | WO | disclosed |
| EP-3770148-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |