Sugi Predict

Sugi Predict / Compounds / SCHEMBL80480

SCHEMBL80480

SCHEMBL80480

CCOC(=O)[C@H]1CCC(=O)N1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.58
▸ GAA P10253 2/20 0.52
▸ TSHR P16473 1/20 0.44
▸ CNR1 P21554 1/20 0.41
▸ DAGLA Q9Y4D2 1/20 0.41
▸ ALDH1A1 P00352 4/20 0.38
▸ MAPT P10636 3/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ POLB P06746 1/20 0.37
▸ PPM1B O75688 1/20 0.37
▸ PTPN1 P18031 1/20 0.37
▸ PPP1CC P36873 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL815103 1.00 LMNA (0.58) LMNAGAATSHRCNR1DAGLA
SCHEMBL905284 1.00 LMNA (0.58) LMNAGAATSHRCNR1DAGLA
Hydrochloric Acid SCHEMBL29400035 0.98 LMNA (0.57) LMNAGAATSHRCNR1DAGLA
Pidolic Acid SCHEMBL14859342 0.94 LMNA (0.53) LMNAGAATSHRCNR1DAGLA
Isopropyl Alcohol SCHEMBL28077462 0.94 LMNA (0.53) LMNAGAATSHRCNR1DAGLA
SCHEMBL15265428 0.90 LMNA (0.49) LMNAGAATSHRALDH1A1MAPT
SCHEMBL5992612 0.90 LMNA (0.49) LMNAGAATSHRALDH1A1MAPT
SCHEMBL13106060 0.90 LMNA (0.49) LMNAGAATSHRALDH1A1MAPT
SCHEMBL3066907 0.88 LMNA (0.48) LMNAGAATSHRALDH1A1MAPT
SCHEMBL7381519 0.87 LMNA (0.47) LMNAGAATSHRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109953367-B Cistanche extracting solution and preparation method, composition and application thereof 内蒙古昆明卷烟有限责任公司 2022-08-02 — — CN claimed
EP-2331524-A1 HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES Bayer CropScience AG (DE) 2011-06-15 — — EP claimed
WO-2010025831-A1 HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-03-11 — — WO claimed
CN-122029171-A Small molecule inhibitors of KRAS proteins 默沙东有限责任公司 2026-05-12 — — CN disclosed
US-20260035386-A1 SMALL MOLECULE INHIBITORS OF KRAS PROTEINS MERCK SHARP & DOHME LLC (US) 2026-02-05 — — US disclosed
US-12466840-B2 Small molecule inhibitors of KRAS proteins MERCK SHARP & DOHME LLC (US) 2025-11-11 — — US disclosed
US-20250136615-A1 SMALL MOLECULE INHIBITORS OF KRAS PROTEINS MERCK SHARP & DOHME LLC 2025-05-01 — — US disclosed
WO-2025085748-A1 SMALL MOLECULE INHIBITORS OF KRAS PROTEINS MERCK SHARP & DOHME LLC (US) 2025-04-24 — — WO disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
CN-114805365-B Factor XIA new macrocycles carrying non-aromatic P2' groups 百时美施贵宝公司 2024-07-23 — — CN disclosed
US-20240239788-A1 SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT TAIHO PHARMACEUTICAL CO., LTD. (JP) 2024-07-18 — — US disclosed
WO-2007064749-A1 COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES SCHERING CORPORATION (US) 2007-06-07 — — WO disclosed
WO-2007042239-A1 PROLINAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS GLAXO GROUP LIMITED (GB) 2007-04-19 — — WO disclosed
WO-2007042240-A1 QUATERNARY ALPHA-AMINOCARBOXAMIDE DERIVATIVES AS MODULATORS OF VOLTAGE-GATED SODIUM CHANNELS GLAXO GROUP LIMITED (GB) 2007-04-19 — — WO disclosed
WO-2007042421-A1 IMIDAZO BENZODIAZEPINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2007-04-19 — — WO disclosed
WO-2007042250-A1 PROLINAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS GLAXO GROUP LIMITED (GB) 2007-04-19 — — WO disclosed
US-20070082890-A1 Substituted imidazo-[1,5-a][1,2,4]triazolo[1,5-d][1,4] benzodiazepine derivatives BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2007-04-12 — — US disclosed
US-20060178366-A1 Compounds for the treatment of inflammatory disorders SCHERING CORPORATION 2006-08-10 — — US disclosed
US-20060178366-A1 Compounds for the treatment of inflammatory disorders SCHERING CORPORATION 2006-08-10 — — US disclosed
WO-2002014261-A2 4-SUBSTITUTED D-GLUTAMIC ACID DERIVATIVES FOR USE AS ANTIBIOTIC ELI LILLY AND COMPANY (US) 2002-02-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12466840-B2 Small molecule inhibitors of KRAS proteins KRAS, NRAS, HRAS LMNA 3053/4885GAA 1320/4885TSHR 4523/4885
US-20260035386-A1 SMALL MOLECULE INHIBITORS OF KRAS PROTEINS KRAS, NRAS, APC LMNA 2262/4885GAA 2852/4885TSHR 4634/4885
US-20240239788-A1 SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT KRAS, NRAS, HRAS LMNA 4027/4885GAA 1240/4885TSHR 4424/4885
US-20060178366-A1 Compounds for the treatment of inflammatory disorders MMP12, ADAMTS1, TNF LMNA 353/4885GAA 67/4885TSHR 3764/4885
US-20250136615-A1 SMALL MOLECULE INHIBITORS OF KRAS PROTEINS KRAS, NRAS, HRAS LMNA 3053/4885GAA 1320/4885TSHR 4523/4885
US-20070082890-A1 Substituted imidazo-[1,5-a][1,2,4]triazolo[1,5-d][1,4] benzodiazepine derivatives GABRA5, GABRA1, GABRA4 LMNA 3824/4885GAA 1252/4885TSHR 481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.