SCHEMBL905284

SCHEMBL905284

CCOC(=O)[C@@H]1CCC(=O)N1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
GAA P10253 2/20 0.52
TSHR P16473 1/20 0.44
CNR1 P21554 1/20 0.41
DAGLA Q9Y4D2 1/20 0.41
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.37
PPM1B O75688 1/20 0.37
PTPN1 P18031 1/20 0.37
PPP1CC P36873 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL815103 1.00 LMNA (0.58) LMNAGAATSHRCNR1DAGLA
SCHEMBL80480 1.00 LMNA (0.58) LMNAGAATSHRCNR1DAGLA
Hydrochloric Acid SCHEMBL29400035 0.98 LMNA (0.57) LMNAGAATSHRCNR1DAGLA
Pidolic Acid SCHEMBL14859342 0.94 LMNA (0.53) LMNAGAATSHRCNR1DAGLA
Isopropyl Alcohol SCHEMBL28077462 0.94 LMNA (0.53) LMNAGAATSHRCNR1DAGLA
SCHEMBL15265428 0.90 LMNA (0.49) LMNAGAATSHRALDH1A1MAPT
SCHEMBL5992612 0.90 LMNA (0.49) LMNAGAATSHRALDH1A1MAPT
SCHEMBL13106060 0.90 LMNA (0.49) LMNAGAATSHRALDH1A1MAPT
SCHEMBL3066907 0.88 LMNA (0.48) LMNAGAATSHRALDH1A1MAPT
SCHEMBL7381519 0.87 LMNA (0.47) LMNAGAATSHRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113072615-B Preparation method of vipatavir intermediate 上海法默生物科技有限公司 2023-01-10 CN claimed
CN-113072615-A Preparation method of vipatavir intermediate 上海法默生物科技有限公司 2021-07-06 CN claimed
CN-110498762-A One kind (2S, 5R) -5- [(benzyloxy) amino]-piperidines -2- Ethyl formate synthetic method QILU TIANHE PHARMACEUTICAL CO LTD 2019-11-26 CN claimed
WO-2019214838-A1 USE OF AN ALCOHOL-CONTAINING COMPOSITION FOR IMPROVING THE SKIN BARRIER FUNCTION EVIDERM INSTITUTE AB (SE) 2019-11-14 WO claimed
CN-109965340-A A kind of preparation method and application of Herba Cistanches extracting solution 内蒙古昆明卷烟有限责任公司 2019-07-05 CN claimed
CN-109953367-A A kind of Herba Cistanches extracting solution and preparation method thereof, composition and application 内蒙古昆明卷烟有限责任公司 2019-07-02 CN claimed
CN-107383025-B The preparation method of endocyclic compound 吉林凯莱英医药化学有限公司 2019-04-26 CN claimed
EP-2766050-B1 PROCESS FOR THE PREPARATION OF HYPERPOLARIZED DERIVATIVES FOR USE IN MRI ANALYSIS BRACCO IMAGING SPA (IT) 2018-09-05 EP claimed
CN-107383025-A The preparation method of endocyclic compound 吉林凯莱英医药化学有限公司 2017-11-24 CN claimed
US-9511154-B2 Process for the preparation of hyperpolarized derivatives for use in MRI analysis BRACCO IMAGING S.P.A. (IT) 2016-12-06 US claimed
US-20100163070-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE L'OREAL S.A. (FR) 2010-07-01 US claimed
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342055-B1 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1994-01-12 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
US-5137714-A Anhydrous cosmetic composition comprising stable lower alkyl esters of pyroglutamic acid UNILEVER PATENT HOLDINGS B.V. (NL) 1992-08-11 US claimed
EP-0342054-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342056-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342055-A2 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed