Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.70 |
| ▸ | HCRTR1 | O43613 | 16/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23032510 | 0.96 | AGTR2 (0.65) | AGTR2HCRTR1HCRTR2HCAR2 | |
| SCHEMBL21400059 | 0.83 | AGTR2 (1.00) | AGTR2 | |
| SCHEMBL23032508 | 0.81 | AGTR2 (0.47) | AGTR2SLC6A7 | |
| SCHEMBL23032405 | 0.80 | AGTR2 (0.91) | AGTR2 | |
| SCHEMBL29931593 | 0.75 | AGTR2 (0.47) | AGTR2HCRTR1HCRTR2SLC6A7 | |
| SCHEMBL23032082 | 0.73 | ALDH1A1 (0.44) | AGTR2 | |
| SCHEMBL22917328 | 0.72 | AGTR2 (0.60) | AGTR2 | |
| SCHEMBL21400356 | 0.71 | AGTR2 (0.79) | AGTR2 | |
| SCHEMBL23032524 | 0.70 | AGTR2 (0.68) | AGTR2HCRTR1HCRTR2 | |
| SCHEMBL2369924 | 0.70 | AGTR2 (0.48) | AGTR2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3770148-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |