Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548002 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19LMNAACHE | |
| SCHEMBL20547967 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19LMNAACHE | |
| SCHEMBL29929381 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19LMNAACHE | |
| SCHEMBL28910814 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19LMNAACHE | |
| SCHEMBL21069711 | 0.76 | HPGD (0.46) | CYP1A2CYP2C9CYP2C19LMNAHPGD | |
| SCHEMBL6473079 | 0.76 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19LMNAACHE | |
| SCHEMBL31419834 | 0.75 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19LMNAACHE | |
| SCHEMBL9053482 | 0.75 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19LMNAACHE | |
| SCHEMBL28437659 | 0.75 | HPGD (0.56) | HPGDALDH1A1MAPK1HTR1AHTR7 | |
| SCHEMBL10291206 | 0.74 | DHFR (0.48) | CYP1A2CYP2C9CYP2C19LMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024543-A1 | NOVEL PENAM DERIVATIVE OR SALT THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF | FUJIFILM CORPORATION (JP) | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024543-A1 | NOVEL PENAM DERIVATIVE OR SALT THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF | CFTR, SLC11A2, SLC20A1 | CYP1A2 4378/4885CYP2C9 2283/4885CYP2C19 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.