Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | WDR5 | P61964 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 4/20 | 0.37 |
| ▸ | TPH2 | Q8IWU9 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19507225 | 0.94 | WDR5 (0.46) | ALDH1A1LMNAWDR5NPC1RAB9A | |
| SCHEMBL16741185 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAWDR5NPC1RAB9A | |
| SCHEMBL871216 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAWDR5NPC1RAB9A | |
| SCHEMBL8188906 | 0.81 | LMNA (0.47) | ALDH1A1LMNAWDR5NPC1RAB9A | |
| SCHEMBL25060981 | 0.80 | LMNA (0.46) | ALDH1A1LMNAWDR5NPC1RAB9A | |
| SCHEMBL18121425 | 0.80 | WDR5 (0.44) | ALDH1A1LMNAWDR5NPC1RAB9A | |
| SCHEMBL25061139 | 0.80 | LMNA (0.46) | ALDH1A1LMNAWDR5NPC1RAB9A | |
| SCHEMBL23349372 | 0.80 | LMNA (0.46) | ALDH1A1LMNAWDR5NPC1RAB9A | |
| SCHEMBL2608601 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAWDR5NPC1RAB9A | |
| SCHEMBL21946945 | 0.77 | LMNA (0.44) | ALDH1A1LMNAWDR5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021016333-A1 | ARYL SULFONAMIDES AS SMALL MOLECULE STAT3 INHIBITORS | UNIVERSITY OF HAWAII (US) | 2021-01-28 | — | — | WO | disclosed |