Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1412161 | 1.00 | NAAA (0.47) | NAAANPSR1RAD52FAAHDGKA | |
| Bromide SCHEMBL2761053 | 1.00 | NAAA (0.47) | NAAANPSR1RAD52FAAHDGKA | |
| Bromide SCHEMBL2293053 | 0.99 | NAAA (0.45) | NAAANPSR1RAD52FAAHDGKA | |
| SCHEMBL2782995 | 0.97 | NAAA (0.46) | NAAANPSR1RAD52FAAHDGKA | |
| Bromide SCHEMBL2296147 | 0.94 | MEN1 (0.43) | NAAADGKAMEN1KMT2AESR1 | |
| SCHEMBL2288344 | 0.93 | MEN1 (0.44) | NAAADGKAMEN1KMT2AESR1 | |
| Bromide SCHEMBL2760616 | 0.88 | ALDH1A1 (0.43) | NAAANPSR1MEN1KMT2AESR1 | |
| Bromide SCHEMBL2291109 | 0.86 | MEN1 (0.37) | NAAADGKAMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL1412107 | 0.86 | NAAA (0.47) | NAAANPSR1RAD52FAAHDGKA | |
| Hydrochloric Acid SCHEMBL1412122 | 0.86 | NAAA (0.47) | NAAANPSR1RAD52FAAHDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2183220-B1 | BIODEGRADABLE SOLVENTS FOR THE CHEMICAL INDUSTRY | UNIV DUBLIN CITY (IE) | 2016-11-09 | — | — | EP | disclosed |
| US-8541598-B2 | Biodegradable solvents for the chemical industry | DUBLIN CITY UNIVERSITY (IE) | 2013-09-24 | — | — | US | disclosed |
| US-20110201824-A1 | BIODEGRADABLE SOLVENTS FOR THE CHEMICAL INDUSTRY | DUBLIN CITY UNIVERSITY (IE) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201824-A1 | BIODEGRADABLE SOLVENTS FOR THE CHEMICAL INDUSTRY | TIMM9, B2M, TIMM44 | NAAA 3748/4885NPSR1 3480/4885RAD52 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.