SCHEMBL2782995

SCHEMBL2782995

CCCCCOC(=O)CN1C=CN(C)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.46
NPSR1 Q6W5P4 2/20 0.41
RAD52 P43351 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
FAAH O00519 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
MAPK1 P28482 2/20 0.39
MAPT P10636 2/20 0.39
HTR2C P28335 1/20 0.39
TSHR P16473 3/20 0.39
DGKA P23743 1/20 0.39
ALOX15 P16050 1/20 0.39
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
ESR1 P03372 1/20 0.37
AKR1C4 P17516 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL2293053 0.98 NAAA (0.45) NAAANPSR1RAD52MEN1KMT2A
Bromide SCHEMBL2761053 0.97 NAAA (0.47) NAAANPSR1RAD52MEN1KMT2A
Bromide SCHEMBL2292017 0.97 NAAA (0.47) NAAANPSR1RAD52MEN1KMT2A
Bromide SCHEMBL1412161 0.97 NAAA (0.47) NAAANPSR1RAD52MEN1KMT2A
SCHEMBL2288344 0.95 MEN1 (0.44) NAAAMEN1KMT2AL3MBTL1MAPK1
Bromide SCHEMBL2296147 0.94 MEN1 (0.43) NAAAMEN1KMT2AL3MBTL1MAPK1
Bromide SCHEMBL2760616 0.88 ALDH1A1 (0.43) NAAANPSR1MEN1KMT2AL3MBTL1
Bromide SCHEMBL2291109 0.86 MEN1 (0.37) NAAAMEN1KMT2AL3MBTL1TSHR
Hydrochloric Acid SCHEMBL1412107 0.85 NAAA (0.47) NAAANPSR1RAD52MEN1KMT2A
Hydrochloric Acid SCHEMBL1412122 0.85 NAAA (0.47) NAAANPSR1RAD52MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2223915-A1 Ionic liquid solvents Dublin City University (IE) 2010-09-01 EP disclosed