SCHEMBL22921153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22921138	0.83	NPC1 (0.37)	NPC1MAPTTRPV1CYP2A6MAOA
	SCHEMBL19165370	0.82	MAPT (0.38)	NPC1MAPTTRPV1CYP2A6MAOA
	SCHEMBL804832	0.82	MAPT (0.50)	NPC1MAPTMAOARAB9AHPGD
	SCHEMBL22921140	0.79	NPC1 (0.34)	NPC1MAPTTRPV1CYP2A6MAOA
	SCHEMBL17789232	0.79	MAPT (0.50)	NPC1MAPTMAOARAB9AHPGD
	SCHEMBL30876951	0.79	MAPT (0.50)	NPC1MAPTMAOARAB9AHPGD
	SCHEMBL17789233	0.78	MAPT (0.44)	NPC1MAPTMAOARAB9AHPGD
	SCHEMBL18803772	0.78	PLA2G2A (0.50)	NPC1MAPTRAB9AHPGDSMN1; SMN2
	SCHEMBL22136664	0.76	PLA2G2A (0.42)	NPC1MAPTMAOARAB9AHPGD
	SCHEMBL22921169	0.76	CYP2A6 (0.55)	MAPTTRPV1CYP2A6HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.