SCHEMBL17789232

SCHEMBL17789232

Brc1cc(Br)cc(-c2ccc3oc4ccccc4c3c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MEN1 O00255 2/20 0.50
NPC1 O15118 2/20 0.50
KMT2A Q03164 2/20 0.50
RAB9A P51151 1/20 0.50
AHR P35869 2/20 0.46
TNKS O95271 1/20 0.45
PLA2G2A P14555 4/20 0.43
PLA2G4A P47712 4/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30876951 1.00 MAPT (0.50) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL804832 0.96 MAPT (0.50) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL18803772 0.92 PLA2G2A (0.50) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL17806987 0.89 AHR (0.50) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL25381394 0.89 KDM4E (0.44) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL17789233 0.89 MAPT (0.44) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL26434891 0.89 AHR (0.47) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL30542090 0.89 KDM4E (0.44) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL805010 0.88 GABRP (0.56) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL29632081 0.88 GABRP (0.56) MAPTKDM4EALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136623-A1 LIGHT EMITTING ELEMENT, FUSED POLYCYCLIC COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2025-05-01 US disclosed
US-20240138170-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-04-25 US disclosed
WO-2017123008-A1 ORGANIC LIGHT-EMITTING DEVICE, ORGANIC LIGHT-EMITTING DISPLAY DEVICE, AND COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE 덕산네오룩스 주식회사 2017-07-20 WO disclosed
US-20160155953-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-02 US disclosed
US-20160155953-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136623-A1 LIGHT EMITTING ELEMENT, FUSED POLYCYCLIC COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME NR2E3, ESR1, CPNE4 MAPT 2361/4885KDM4E 1473/4885ALDH1A1 99/4885
US-20160155953-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME RPS4X, OR10J3, RPS4Y1 MAPT 3528/4885KDM4E 1251/4885ALDH1A1 946/4885
US-20240138170-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME LEF1, NFE2L2, ELP1 MAPT 3274/4885KDM4E 951/4885ALDH1A1 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.