Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22349877 | 0.88 | CASP2 (0.37) | CASP2ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL24340774 | 0.85 | CNR1 (0.40) | CASP2ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL13629818 | 0.85 | CASP2 (0.47) | CASP2ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL24340576 | 0.85 | CASP2 (0.33) | CASP2 | |
| SCHEMBL22923596 | 0.84 | CASP2 (0.55) | CASP2ALDH1A1SMN1; SMN2NAAA | |
| SCHEMBL21538798 | 0.84 | CASP2 (0.43) | CASP2ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL20362595 | 0.82 | CASP2 (0.47) | CASP2ALDH1A1HPGDSMN1; SMN2NAAA | |
| SCHEMBL22349883 | 0.80 | GBA1 (0.33) | CASP2 | |
| SCHEMBL23815863 | 0.79 | DNM1 (0.37) | CASP2TSHRNAAA | |
| SCHEMBL22349882 | 0.79 | CASP2 (0.31) | CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056273-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |
| WO-2021013693-A1 | ANTIBODY DRUG CONJUGATES (ADCS) WITH NAMPT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-01-28 | — | — | WO | disclosed |