Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923591 | 0.89 | CASP2 (0.41) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL24340774 | 0.86 | CNR1 (0.40) | CASP2ALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL22923592 | 0.85 | CASP2 (0.35) | CASP2NAAAEPHX1MEN1ALDH1A1 | |
| SCHEMBL22923595 | 0.84 | CASP2 (0.38) | CASP2NAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL23815863 | 0.84 | DNM1 (0.37) | CASP2NAAADNM1CNR1 | |
| SCHEMBL22349877 | 0.83 | CASP2 (0.37) | CASP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL24340576 | 0.83 | CASP2 (0.33) | CASP2CNR1 | |
| SCHEMBL22349883 | 0.81 | GBA1 (0.33) | CASP2 | |
| SCHEMBL25082958 | 0.81 | EPHX1 (0.43) | CASP2NAAAEPHX1FAAHCNR1 | |
| SCHEMBL25083035 | 0.81 | EPHX1 (0.43) | CASP2NAAAEPHX1FAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021013693-A1 | ANTIBODY DRUG CONJUGATES (ADCS) WITH NAMPT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-01-28 | — | — | WO | disclosed |