Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 2/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923882 | 0.89 | MEN1 (0.44) | KDM4EMCHR1DRD2DRD3HPGD | |
| SCHEMBL22923912 | 0.80 | LMNA (0.42) | KDM4ELMNAKCNH2 | |
| SCHEMBL22923869 | 0.78 | MTNR1A (0.42) | KDM4ELMNANPC1HPGDRAB9A | |
| SCHEMBL22923934 | 0.76 | KDM4E (0.39) | KDM4ELMNAKCNH2 | |
| SCHEMBL22923941 | 0.75 | MAPT (0.38) | KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL30367422 | 0.75 | LMNA (0.51) | KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL22923858 | 0.72 | LMNA (0.49) | KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL22923879 | 0.72 | LMNA (0.49) | KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL25422029 | 0.71 | KMT2A (0.42) | KDM4EALDH1A1KCNH2HRH3 | |
| SCHEMBL22923870 | 0.71 | MEN1 (0.48) | KDM4ELMNANPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012717-A1 | ANTITUMOR COMPOUND USED AS AXL INHIBITOR AND USE THEREOF | 南京华威医药科技集团有限公司 | 2021-01-28 | — | — | WO | disclosed |