Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923912 | 0.93 | LMNA (0.42) | KDM4ELMNAHTR7RECQLL3MBTL1 | |
| SCHEMBL22923932 | 0.89 | MEN1 (0.43) | KDM4ELMNAABCB1MEN1KMT2A | |
| SCHEMBL22923869 | 0.77 | MTNR1A (0.42) | KDM4ELMNAABCB1MEN1KMT2A | |
| SCHEMBL22923883 | 0.76 | KDM4E (0.40) | KDM4ELMNAKCNH2 | |
| SCHEMBL22923941 | 0.74 | MAPT (0.38) | KDM4ELMNARECQLL3MBTL1MEN1 | |
| SCHEMBL30367422 | 0.74 | LMNA (0.51) | KDM4ELMNARECQLL3MBTL1ABCB1 | |
| SCHEMBL22923879 | 0.72 | LMNA (0.49) | KDM4ELMNARECQLL3MBTL1ABCB1 | |
| SCHEMBL22923858 | 0.72 | LMNA (0.49) | KDM4ELMNARECQLL3MBTL1ABCB1 | |
| SCHEMBL22923863 | 0.69 | LMNA (0.52) | KDM4ELMNARECQLL3MBTL1ABCB1 | |
| SCHEMBL22923904 | 0.69 | METAP2 (0.47) | KDM4ELMNAHTR7RECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012717-A1 | ANTITUMOR COMPOUND USED AS AXL INHIBITOR AND USE THEREOF | 南京华威医药科技集团有限公司 | 2021-01-28 | — | — | WO | disclosed |