Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31638876 | 0.82 | CYP3A4 (0.63) | POLBKMT2ACYP3A4TDP1MAPT | |
| SCHEMBL28502339 | 0.81 | POLB (0.48) | POLBKMT2ACYP3A4TDP1MAPT | |
| SCHEMBL9720555 | 0.78 | FASN (0.46) | POLBKMT2ACYP3A4TDP1MAPT | |
| SCHEMBL31257914 | 0.77 | POLB (0.52) | POLBKMT2ACYP3A4MAPTMEN1 | |
| SCHEMBL14094952 | 0.76 | CYP3A4 (0.68) | POLBKMT2ACYP3A4TDP1MAPT | |
| SCHEMBL347917 | 0.76 | CYP3A4 (0.51) | POLBKMT2ACYP3A4MAPTHPGD | |
| SCHEMBL30798286 | 0.74 | POLB (0.46) | POLBCYP3A4TDP1MAPTHPGD | |
| SCHEMBL5329670 | 0.74 | MAP2K1 (0.50) | POLBCYP3A4TDP1MAPTHPGD | |
| SCHEMBL2024212 | 0.74 | POLB (0.46) | POLBCYP3A4TDP1MAPTHPGD | |
| SCHEMBL1004368 | 0.74 | ACHE (0.48) | POLBCYP3A4TDP1MKNK2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113646319-A | C11-ring-substituted 13-membered macrolides and their use | 齐卡尼治疗股份有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-113573779-A | C10-alkylene substituted 13-membered macrolides and their use | 齐卡尼治疗股份有限公司 | 2021-10-29 | — | — | CN | disclosed |
| WO-2021015177-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | 出光興産株式会社 | 2021-01-28 | — | — | WO | disclosed |