Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.48 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996063 | 0.85 | FAAH (0.63) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL25832795 | 0.81 | EPHX2 (0.44) | EPHX2FAAHTERTPTPN1PPARG | |
| SCHEMBL19996043 | 0.81 | PPARG (0.74) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL19996056 | 0.81 | PPARG (0.74) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL19996057 | 0.81 | PPARG (0.74) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL14213048 | 0.81 | TERT (0.54) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL24076765 | 0.80 | ALDH1A1 (0.59) | — | |
| Ethylene SCHEMBL28467416 | 0.80 | TSHR (0.59) | EPHX2FAAHPPARA | |
| Ethylene SCHEMBL820333 | 0.80 | TSHR (0.59) | EPHX2FAAHPPARA | |
| Ethylene SCHEMBL11903935 | 0.80 | TSHR (0.59) | EPHX2FAAHPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081058-A1 | COMPOSITIONS, METHODS AND USES OF MESSENGER RNA | TRANSLATE BIO, INC. (US) | 2021-04-29 | — | — | WO | disclosed |
| WO-2021016430-A1 | STABLE COMPOSITIONS OF MRNA-LOADED LIPID NANOPARTICLES AND PROCESSES OF MAKING | TRANSLATE BIO, INC. (US) | 2021-01-28 | — | — | WO | disclosed |