Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417061 | 0.79 | PPARA (0.38) | MMP8 | |
| SCHEMBL12117980 | 0.76 | MMP8 (0.34) | MMP8 | |
| SCHEMBL85558 | 0.74 | CA1 (0.44) | CA1CA2 | |
| SCHEMBL24861557 | 0.74 | CA1 (0.35) | CA1CA2 | |
| SCHEMBL24961334 | 0.73 | RIPK1 (0.37) | CA1 | |
| SCHEMBL24443113 | 0.71 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL14417066 | 0.70 | MMP8 (0.40) | MMP8 | |
| SCHEMBL12461121 | 0.70 | MMP8 (0.53) | CA2MMP8 | |
| SCHEMBL13799203 | 0.69 | GAA (0.33) | CA1CA2 | |
| SCHEMBL12304211 | 0.69 | ALDH1A1 (0.45) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447452-B2 | Agonists of peroxisome proliferator-activated receptor alpha and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210024469-A1 | AGONISTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024469-A1 | AGONISTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA AND METHODS OF USE | PPARG, PPARA, PPARD | CA1 4832/4885CA2 4472/4885MMP8 236/4885 |
| US-11447452-B2 | Agonists of peroxisome proliferator-activated receptor alpha and methods of use | PPARG, PPARA, PPARD | CA1 4832/4885CA2 4472/4885MMP8 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.