Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | SHBG | P04278 | 1/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29574422 | 1.00 | LMNA (0.77) | LMNAHTTSMN1; SMN2ESR1SHBG | |
| SCHEMBL3958571 | 0.87 | LMNA (1.00) | LMNAHTTSMN1; SMN2ESR1SHBG | |
| SCHEMBL17838467 | 0.87 | LMNA (0.58) | LMNAHTTSMN1; SMN2ESR1SHBG | |
| SCHEMBL18176742 | 0.85 | LMNA (0.69) | LMNAHTTSMN1; SMN2ESR1SHBG | |
| SCHEMBL312243 | 0.82 | ESR1 (1.00) | LMNAHTTSMN1; SMN2ESR1SHBG | |
| SCHEMBL30503014 | 0.82 | ESR1 (1.00) | LMNAHTTSMN1; SMN2ESR1SHBG | |
| SCHEMBL11566 | 0.81 | MAPT (0.53) | LMNAHTTSMN1; SMN2ESR1SHBG | |
| SCHEMBL22672221 | 0.80 | ESR1 (0.81) | LMNAHTTSMN1; SMN2ESR1SHBG | |
| SCHEMBL30497946 | 0.79 | ESR1 (0.80) | LMNAHTTSMN1; SMN2ESR1SHBG | |
| SCHEMBL146018 | 0.79 | ESR1 (0.80) | LMNAHTTSMN1; SMN2ESR1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014915-B2 | Selective estrogen receptor degrader | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2021-05-25 | — | — | US | disclosed |
| US-20210024504-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADER | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2021-01-28 | — | — | US | disclosed |
| WO-2021014386-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADER | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2021-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024504-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADER | ESR1, GPER1, ESR2 | LMNA 4259/4885HTT 4080/4885SMN1; SMN2 2484/4885 |
| US-11014915-B2 | Selective estrogen receptor degrader | ESR1, GPER1, ESR2 | LMNA 4259/4885HTT 4080/4885SMN1; SMN2 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.