SCHEMBL22925147

SCHEMBL22925147

CN/N=C/c1cc(F)cc(F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
ALDH1A1 P00352 3/20 0.42
GAA P10253 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MAOB P27338 1/20 0.37
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
MPO P05164 2/20 0.36
NPC1 O15118 5/20 0.34
RAB9A P51151 5/20 0.34
PKM P14618 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPK1 P28482 1/20 0.34
THPO P40225 1/20 0.34
CHRM5 P08912 1/20 0.34
GRM5 P41594 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23616056 0.79 NPC1 (0.62) LMNAALDH1A1GAAKDM4EMAOB
SCHEMBL15985661 0.78 ALDH1A1 (0.40) LMNAALDH1A1GAAKDM4EMPO
SCHEMBL16355427 0.77 GAA (0.57) LMNAALDH1A1GAAKDM4EMPO
SCHEMBL616031 0.76 GAA (0.33) LMNAALDH1A1GAAKDM4ENPC1
SCHEMBL616030 0.76 GAA (0.33) LMNAALDH1A1GAAKDM4ENPC1
SCHEMBL23709478 0.72 NPC1 (0.49) LMNAALDH1A1GAAKDM4ENPC1
SCHEMBL16609588 0.72 KDM4E (0.68) LMNAALDH1A1GAAKDM4EMPO
SCHEMBL22925017 0.71 LMNA (0.66) LMNAALDH1A1GAAKDM4ENPC1
SCHEMBL4112809 0.71 CYP1A2 (0.49) MAOBNPC1RAB9ACYP1A2CYP3A4
SCHEMBL22925138 0.70 ALDH1A1 (0.44) LMNAALDH1A1GAAKDM4EMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021012264-A1 TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 东莞市东阳光农药研发有限公司 2021-01-28 WO disclosed