Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925138 | 0.85 | ALDH1A1 (0.44) | NPC1RAB9AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23616071 | 0.83 | ALDH1A1 (0.43) | NPC1RAB9AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22925145 | 0.80 | ALDH1A1 (0.41) | NPC1RAB9AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20529052 | 0.80 | AMY1A (0.56) | NPC1RAB9AALDH1A1GAAKDM4E | |
| SCHEMBL17211853 | 0.78 | NPC1 (0.66) | NPC1RAB9AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17211961 | 0.78 | ALDH1A1 (0.54) | NPC1RAB9AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16609588 | 0.78 | KDM4E (0.68) | NPC1RAB9AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15985661 | 0.78 | ALDH1A1 (0.40) | NPC1RAB9AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16355427 | 0.77 | GAA (0.57) | NPC1RAB9AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22550282 | 0.77 | NFE2L2 (0.50) | NPC1RAB9AMAPK1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3188722-B1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-08-04 | — | — | EP | disclosed |