Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 9/20 | 0.45 |
| ▸ | FLT1 | P17948 | 8/20 | 0.45 |
| ▸ | FLT4 | P35916 | 7/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.42 |
| ▸ | VCP | P55072 | 4/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925990 | 0.89 | ALOX5 (0.51) | ALOX5KDRFLT1FLT4VCP | |
| SCHEMBL22925574 | 0.86 | ALOX5 (0.57) | ALOX5KDRFLT1FLT4IMPDH2 | |
| SCHEMBL22925668 | 0.79 | TRPV1 (0.46) | ALOX5KDRFLT1FLT4VCP | |
| SCHEMBL28733809 | 0.78 | VCP (0.56) | ALOX5KDRFLT1FLT4VCP | |
| SCHEMBL24637048 | 0.75 | ALOX5 (0.55) | ALOX5KDRFLT1FLT4VCP | |
| SCHEMBL22925577 | 0.74 | ALOX5 (0.53) | ALOX5KDRFLT1FLT4DGAT1 | |
| SCHEMBL24636900 | 0.70 | KDR (0.51) | ALOX5KDRFLT1FLT4IMPDH2 | |
| SCHEMBL29696307 | 0.70 | TRPV1 (0.46) | ALOX5KDRFLT1FLT4VCP | |
| SCHEMBL22925770 | 0.70 | TRPV1 (0.46) | ALOX5KDRFLT1FLT4VCP | |
| SCHEMBL14134239 | 0.69 | KDR (0.66) | ALOX5KDRFLT1FLT4IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |